International Mammalian Genome Society

The 16th International Mouse Genome Conference (2002)

Oral Presentation

Sunday 17 November

17:30 - 17:45 HRS

Rat Genome Database: A comparative genomics platform for rat, mouse And human

PJ Tonellato
Bioinformatics Research Center

Co-Authors: 1) Twigger S, 3) Eppig J, 1) Lu J, 1) Shimoyama M, 1) Pasko D, 1) Bromberg S, 1) Ginster J, 1) Chen CF, 1) Nigam R, 1) Gopinathrao G, 1) Ramachandran H, 2) Kwitek-Black A, 4) Maglott D, 4) Schuler G, 5) Stahl F, 5) Levan G, 2) Jacob H
Institutions: 1) Bioinformatics Research Center, and 2) Human and Molecular Genetics Center, Medical College of Wisconsin; 3) The Jackson Laboratory,; 4) National Center for Biotechnology Information, NIH, 5) CMB Genetics Lundberg Laboratory, Gothenburg University

The Rat Genome Database (RGD, is a resource for comprehensive curated physiological and genomic data for rat. RGD seeks to aid researchers in using the rat as a model organism for human disease by supporting the integratation of large-scale rat genomic studies with ongoing literature curation. Data about rat genes in RGD include homologies to mouse and human genes, gene product identity, gene functions and descriptive information. RGD maintains and curates GO (Gene Ontology) annotations to facilitate physiological genomic studies relating diseases to the genome. In collaboration with the Mouse Genome Database and NCBI, links are made between RGD and MGD, LocusLink and UniGene to increase access to each set of data. RGD provides a variety of tools for researchers, including VCMap, a dynamic sequence-based comparative genomics tool that enables researchers to view mapped genes and sequences and the location of their homologs in rat, mouse and human. Thus RGD is a valuable resource for those working with rat and for researchers in other model organisms wishing to harness the power of comparative genomics and take advantage of the genetic and physiological data in rat to complement and enhance their own work.

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