International Mammalian Genome Society

The 16th International Mouse Genome Conference (2002)


POSTER 74 - MOUSE GENOME INFORMATICS: A COMPREHENSIVE INFORMATION RESOURCE FOR THE LABORATORY MOUSE

LN Ni
Informatics, The Jackson Laboratory

Blake JA, Bult CJ, Ringwald M, Kadin JA, Richardson JE, Eppig JT, and the Mouse Genome Informatics Group
The Jackson Laboratory

The Mouse Genome Informatics (MGI, http://www.informatics.jax.org/) is a comprehensive integrated public information resource for mouse genetics, genomics and biology. It fully integrates information on over 32,000 mouse genes and experimental data from over 77,000 references. MGI provides extensively curated mouse data encompassing mouse gene nomenclature; mutant and strain phenotypes; embryonic gene expression patterns; molecular segments and sequence clusters; genetic, physical, and comparative maps; allelic variations and mammalian homology information. MGI also collaboratively curates data with SWISS-PROT and NCBI/LocusLink and provides extensive curated links with these and other online resources such as GenBank, PubMed and OMIM. One of the fundamental goals of the Mouse Genome Informatics is to functionally annotate the mouse genome. Towards this goal, MGI is actively engaged in the development and application of controlled vocabularies developed by the Gene Ontology consortium to annotate the biology of gene products at the level of their cellular location, the biological processes and their molecular function. Other structured vocabularies of phenotype descriptors and anatomical terms have also been developed to represent phenotypic information and expression patterns on the database.  Additionally, MGI maintains links to SWISS-PROT, InterPro and the Enzyme Commission. These interconnections and classification schemes place the MGI data in the larger biological and analytical context. MGI is supported by NIH grants HG00330, HG02273, HD33745 and DOE grant DE 99ER62850.


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