International Mammalian Genome Society

17th International Mouse Genome Conference

9-12 November 2003, Braunschweig, Germany


Lengger C
GSF National Research Centre for Environment and Health, Neuherberg

Co-Authors: Gailus-Durner V, Steinkamp R, Schäble K F, Pargent W, Tiedemann H, Schneltzer E, Fuchs H, Hrabe de Angelis M
Institutions: GSF National Research Centre for Environment and Health, Neuherberg

The German Mouse Clinic (GMC) is a novel facility for the comprehensive phenotyping of approx. 3000 mice per year.

A commercial hospital information system (designed for human patients) has been adjusted and functionally extended to meet our special needs for GMC data management. This software now provides features including modules for facility management (breeding, resource management), a system for workflow planning and the generation of worklists, a tool to define deliberate groups of mice (e.g. with certain biological attributes) and a pedigree browser. A data retrieval tool enables users to generate adhoc queries without inside knowledge of neither SQL syntax nor the database scheme.

Data output from various sources is automatically parsed by a variety of scripts. Referential integrity checks are performed by central data interfaces running on a communication server automatically while inserting the results of phenotype analysis into the GMC database.

Additionally, file based information (like images, videos etc.) are stored on a separate file server. These files are linked to the mouse data so that they can be called and displayed by the graphical user interface together with other result data. Data import and export from and to Excel sheets is implemented throughout the system.

The software is running on a Win2K-Server. For sake of client platform indepency and central system maintenance, the application is deployed via terminal server technology (Citrix Metaframe). For data storage a commercial RDBMS is being used.

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