International Mammalian Genome Society

17th International Mouse Genome Conference

9-12 November 2003, Braunschweig, Germany


POSTER 154 - COLLECTION, P RESERVATION AND DISTRIBUTION OF MOUSE RESOURCE BY RIKEN BIORESOURCE CENTER --OVERVIEW OF ITS ACTIVITY AND FACILITIES

Yoshiki A
RIKEN BioResource Center

Co-Authors: Nakata H, Ike F, Hiraiwa N, Yoshida-Noro C, Kazuyuki M, Keiji M, Yuichi Obata, Kazuo M
Institutions: RIKEN BioResource Center

Since 2002 fiscal year, Experimental Animal Division of RIKEN BRC has been selected as a core center for experimental animal (mouse) by National BioResource Project operated by the Ministry of Education, Culture, Sports, Science and Technology (MEXT). Our goal is to facilitate scientific research on human being and contribute to the human welfare, and basic biological science. Based on the needs from scientific community, our division focuses on the mouse as the most important resource. The Materials Transfer Agreement was prepared both in Japanese and English for collection and distribution of the mouse strains. 343 strains were newly added in 2002 from universities and research institutes in Japan . Along with 320 mouse strains maintained in our center, 663 strains have been collected and maintained. These mice including inbred, wild mouse-derived, mutant, genetically engineered strains are useful model mouse for the study of cancer, immunity and allergy, endocrine disease, brain and neurological disorder, development and differentiation abnormality, and sensory organ abnormality. Newly collected living strains were rederived to obtain specific pathogen free animals by in vitro fertilization and embryo transfer or cesarean section. Cryopreservation of mouse embryos was carried out and resulted in more than 600 strains cryopreserved in this center. The sperms were also cryopreserved. We will introduce our recent activity including quality control programs of microbiological and genetic monitoring, animal facilities for this project.


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