International Mammalian Genome Society

17th International Mouse Genome Conference

9-12 November 2003, Braunschweig, Germany


ORAL PRESENTATION

TUESDAY 11 NOVEMBER
15:15 – 15:30 HRS

EUMORPHIA – DEVELOPING NEW APPROACHES TO MOUSE PHENOTYPING

Brown SDM
The Eumorphia Consortium

EUMORPHIA is an integrated research programme supported by the EU involving the development of new approaches in phenotyping, mutagenesis and informatics leading to improved characterisation of mouse models for the understanding of human physiology and disease. The project harnesses the expertise and resource of many European mouse genetics centres. The focus is on the development, standardisation and dissemination of primary and secondary phenotyping protocols for all body systems in the mouse. One of the key aims is to improve the reproducibility of phenotype tests and their comparability across different laboratories and to provide access to new and improved phenotyping platforms. An initial goal of EUMORPHIA is to establish a new robust primary screening protocol – the European Comprehensive First Line Phenotyping protocol (ECFLP) – and to integrate this platform with appropriate ontologies for data dissemination and analysis. We will discuss the progress in EUMORPHIA by illustrating the development and validation of the ECFLP and by providing examples of advances in phenotype platforms in specific systems areas.


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