International Mammalian Genome Society

17th International Mouse Genome Conference

9-12 November 2003, Braunschweig, Germany


POSTER 27 - THE ULTIMATE™ ORF BROWSER: ADVANCED SEARCH TOOL AND INFORMATION CENTER FOR THE ULTIMATE™ ORF CLONE COLLECTION

Boyaniwsky T
Invitrogen Corporation, Carlsbad, California

Co-Authors: Parvizi B, Yen J, Liang F
Institutions: Invitrogen Corporation, Carlsbad, California

A major challenge following the sequencing of the human genome is to determine the biological functions of the estimated 30,000 – 50,000 gene transcripts and splicing variants. This requires the biochemical characterization of expressed proteins in many expression systems. In an effort to accelerate the research in functional genomics and protein expression in a high throughput fashion, Invitrogen launched an ORFeome program to provide high-quality sequence verified ORFs (Open Reading Frames) in a Gateway® –compatible entry vector. In order to facilitate researchers to find ORFs in our ORFeome database, we have developed a web based ORFBrowser. This ORFBrowser allows researchers to find the Ultimate™ ORF clone they need, blasting by sequence, searching by keyword, accession number, clone ID, Unigene ID, LocusLink ID or browsing through Gene Ontology (GO) – a dynamic controlled vocabulary used to annotate all eukaryotic genes. Each ORF has been extensively annotated in the format of an ORFCard in six categories: Gene, ORF, Clone Format, Protein, SNP and Genomic links. This information rich ORFCard provides researchers a consolidated approach to verifying clones by viewing the sequence quality and aligning the ORF to public protein sequence, and accessing the latest publicly available information on each ORF with a simple click.


Abstracts * Officers * Bylaws * Application Form * Meeting Calendar * Contact Information * Home * Resources * News and Views * Membership

Base url http://imgs.org
Last modified: Saturday, November 3, 2012