International Mammalian Genome Society

logo18th International Mouse Genome Conference

17-22 October 2004, Seattle, USA


POSTER 102 - THE MOUSE GENE EXPRESSION DATABASE (GXD):  INTEGRATED ACCESS TO EXPRESSION INFORMATION FOR THE LABORATORY MOUSE

Begley DA, Eppig JT, Finger JH, Hayamizu TF, Hill DP, Kadin JA, McCright IJ, Richardson JE, Smith CM, Ringwald M.

The Jackson Laboratory, Bar Harbor, United States

The Gene Expression Database (GXD) collects and integrates gene expression information about the developing laboratory mouse.  By combining diverse types of expression data, GXD provides information about the expression profiles of transcripts and proteins in different mouse strains and mutants, thus enabling insights into the molecular networks underlying developmental and disease processes.  Expression patterns are described using an extensive dictionary of standardized anatomical terms, making it possible to record expression results from assays with differing spatial resolution in a consistent manner.  GXD is integrated with the Mouse Genome Database and interconnected with other community resources, to include expression data in a larger biological and analytical context.  Data is acquired by direct curation from the literature, database downloads and electronic laboratory submissions.  To facilitate the direct submission of data to GXD we have developed the Gene Expression Notebook (GEN).  GEN functions as a laboratory notebook to store and organize expression data, assay details and images for in situ hybridization, immunohistochemistry, RT-PCR and Northern and Western blot experiments.  It also allows the researcher to effortlessly submit selected expression data to GXD.  Capturing these data will further enhance GXD’s utility as a community resource.  GEN is available at http://www.informatics.jax.org/mgihome/GXD/GEN/.  GXD is accessible through the Mouse Genome Informatics web site at http://www.informatics.jax.org/. 

GXD is supported by NIH grant HD 33745.

[an error occurred while processing this directive]