International Mammalian Genome Society

logo18th International Mouse Genome Conference

17-22 October 2004, Seattle, USA


Session 2 – Manipulation of Genome I
Chair: Martin Hrabe de Angelis

RNAi Directed Therapies for Human Viral Hepatitis Infection
Dirk Grimm (Mark Kay)
Department of Pediatrics and Genetics, Stanford University, United States

Manipulation of Genome Papers

Region-Specific Saturated Mutagenesis Using the Sleeping Beauty Transposon System
Takeda J 1, Keng VW 1, Yae K 1, Hayakawa T 1, Mizuno S 1, Uno Y 2, Kokubu C 1, Horie K 1
1 Dept. of Social and Environmental Medicine, Osaka University Graduate School of Medicine, Osaka, Japan, 2 The Institute of Experimental Animal Science, Osaka University, Osaka, Japan

INGENOtyping – An Highly Efficient Approach to Generate Gene Targeted Mouse and Rat Models
Laufs J, Sedlmeier R, Peters T, Huffstadt U, Wattler S, Nehls M 
Ingenium Pharmaceuticals, Martinsried, Germany

Mutations that Cause Heterozygous Eye Defects are Lethal when Homozygous and Model Human Disease
Cross SH 1, Hart AW 1, Morgan JE 1, McKie L 1, West K 1, Schneider JE 2, Bhattacharya S 2, Jackson IJ 1
1 MRC Human Genetics Unit, Edinburgh, United Kingdom, 2 Wellcome Trust Centre for Human Genetics, Oxford, United Kingdom

Haplotype Analysis in Multiple Crosses to Identify a QTL Gene
Wang X, Korstanje R, Higgins D, Paigen B 
The Jackson Laboratory, Bar Harbor, ME, United States

Verne Chapman Memorial Lecture
25 Years of Transgenic Mice: The Metallothionein Perspective
Richard Palmiter
Investigator, Howard Hughes Medical Institute
And Professor of Biochemistry, University of Washington, Seattle, United States

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