International Mammalian Genome Society

logo18th International Mouse Genome Conference

17-22 October 2004, Seattle, USA


Session 8 – Genome Instability and Aging –
Sponsored by the
Ellison Foundation
Chair: John Schimenti

Genome Instability and Aging
George Martin
Professor of Pathology Emeritus, University of Washington, Seattle, United States

Genome Instability and Aging Papers

Chromosomal Instability Leads to Birth Defects and Cancer Predisposition in Recql4-Deficient Mice: A Model of Rothmund-Thomson Syndrome
MannMB, Luo G 
Department of Genetics, Case Western Reserve University and Ireland Cancer Center, University Hospitals of Cleveland, Cleveland, United States

Pinkie, the First Viable Germline Hypomorph Allele of Retinoid X Receptor Alpha, Reveals an Important Role for RXRa in Th2 Development
Du X 1, Bigby T 2, Tabeta K 1, Janssen E 3, Crozat K 1, Mann N 1, Beutler B 1
1 The Scripps Research Institute, La Jolla, United States, 2 VA San Diego Healthcare System and the University of California, San Diego, United States, 3 La Jolla Institute for Allergy and Immunology, La Jolla, United States

Maintaining Telomere and Chromosome Stability Require the Rad51d Homologous Recombination Gene
Smiraldo PG 1, Tarsounas M 3, Gruver AM 1, Osborn JC 1, Munoz P 2, Class A 3,  Blasco MA 2, West SC 3, Pittman DL 1
1 Medical College of Ohio, Toledo, United States, 2 Spanish National Cancer Center, Madrid, Spain, 3 Cancer Research UK, London Research Institute, Hertfordshire, United Kingdom

Studying the Role of the Kinesin-Like Motor Protein, Eg5, in Tumorigenesis, Genome Instability, and Aging
Castillo A , Justice MJ 
Baylor College of Medicine, Houston, United States

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