International Mammalian Genome Society


The 13th International Mouse Genome Conference
October 31-November 3, 1999

Table of Contents * Structure * Bioinformatics * Sequence * Mapping * New Tools * Gene Discovery * Developmental * Mutagenesis * Functional Genomics

Genealogies of Mouse Inbred Strains

Jon A. Beck1,2, Sarah Lloyd1,2, Majid Hafezparast2, Moyha Lennon-Pierce3, Janan T. Eppig3, Michael F. W. Festing4, and Elizabeth M. C. Fisher2. 1MRC Prion Unit and 2Department of Neurogenetics, Imperial College School of Medicine, London, UK; 3The Jackson Laboratory, Bar Harbor, Maine, USA; 4MRC Toxicology Unit, University of Leicester, Leicester, UK

Over 450 mouse inbred strains have been described, providing a wealth of different genotypes and phenotypes for genetic and other studies. As the mouse is the organism of choice for modelling human disease, and as new strains are produced and others become extinct, it is useful periodically to review what is available and how strains are related to each other, particularly in the light of available DNA polymorphism data from microsatellite and other markers. Our poster presents these data and a graphical geneaology chart showing the origins and relationships of inbred mouse strains, 90 years after matings for the first inbred strain, DBA, began.

 


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