International Mammalian Genome Society

The 13th International Mouse Genome Conference
October 31-November 3, 1999

Table of Contents * Structure * Bioinformatics * Sequence * Mapping * New Tools * Gene Discovery * Developmental * Mutagenesis * Functional Genomics

B11 Tools for EST Mapping

Patricia Rodriguez-Tome. Wellcome Trust Genomic Center, Cambridge, UK

Expressed Sequence Tags (ESTs) are cheap, easy and quick to obtain and sample many genes. They are very useful for developing Sequence Tags Sites (STSs) for mapping. However ESTs have many problems and the public EST databases contain all the errors and high redundancy intrinsic to the submitted data. It is often necessary to provide derived views as a better starting point for research.

To help a Mouse European Consortium to build their Radiation Hybrid maps, we have developed a set of tools that help chose the relevant ESTs for mapping:

All the software and databases are published to the Internet with CORBA interfaces to enable flexible global access to the data and services for EST mapping at the EBI.

For more information on the CORBA developments at the EBi please visit


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