International Mammalian Genome Society

The 14th International Mouse Genome Conference (2000)

Table of Contents * Genes, Physical Mapping and Sequencing * Gene Identification * Bioinformatics * Common Resources * RIKEN Session * Functional Genomics * Complex Traits * Mutagenesis * Developmental Genetics and Differentiation * Verne Chapman Memorial Lecture I and II

E5. Protein Interaction Maps

Marc Vidal
Dana-Farber Cancer Institute and Department of Genetics, Harvard Medical School

Until recently, mostly classical genetics and biochemistry were used to investigate how organisms develop, reproduce, behave, age etc… However, the availability of complete genome sequences suggests additional approaches into biological research. Our goal is to generate and interpret comprehensive protein-interaction maps, particularly in C. elegans. Early versions of protein interaction maps and other functional maps, such as those based on global expression profiling, suggest they will help our understanding of the processes that control the biology of living organisms.