International Mammalian Genome Society

The 15th International Mouse Genome Conference (2001)

Table of Contents * Complex Genetics * Developmental Genetics * Gene Annotation * Gene Discovery * Genome Sequencing * Functional Genomics * Mutagenesis * Presentations * Verne Chapman Memorial Lecture

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H. Presentations

VERNE CHAPMAN LECTURE: WILD MICE AS A SOURCE OF GENETIC POLYMORPHISM
Jean-Louis Guénet

MAPPING AND SEQUENCING THE MOUSE GENOME
John D McPherson

LARGE-SCALE SEQUENCING OF THE MOUSE GENOME
Kerstin Lindblad Toh, Brown DG, Ainscough R, Batzoglou S, Birren B, Brent M, Clee C, Jaffe D, Kent J, Lander ES, Linton LM, Marra M, McPherson JD, Mortimore B, Mullikin J, Nusbaum C, Plumb B, Rodgers J, Sekhon M, Stange-Thomann N, Waterston RH, Wylie K, Willey D, Wilson RK, Zody MC

MOUSE AND RAT BAC ENDS QUALITY ASSESSMENT AND SEQUENCE ANALYSES
Shaying Zhao, Shetty J, Shatsman S, Ayodeji B, Geer K, Tsegaye G, Krol M, Gebregeorgis E, Shvartsbeyn A, Russell D, Overton L, Jiang L, Dimitrov G, Tran K, Malek J, Feldblyum T, Nierman W, Fraser CM

COMPARATIVE MAPPING OF HUMAN Chr 21 AND MOUSE Chrs 16 AND 17, AND GENE CONTENT OF TS65DN
Muriel Davisson, Gardiner K, Akeson EC, Bechtel LJ, Fortna A, Slavov D, Schmidt C

UK MOUSE SEQUENCING PROGRAMME
AM Mallon, P Denny, MRM Botcherby, P Gautier, H Hummerich, S Cross, V van Heyningen, N Leaves, J Greystrong, L Greenham, S Jones, K Maggott, S Manjunath, G Strachan, M Strivens, P North, M Campell, G Hunter, G Kimberley, L Cave-Berry, L Mathews, S Simms, S Gregory, R Evans, T Hubbard, R Durbin, M Cadman, R Mc Keone, C Sellick, M Iravani, S White, P Little, I Jackson, J Rogers, RD Campbell, SDM Brown

COMPARATIVE MAPPING AND SEQUENCING: MOUSE AND BEYOND
Jim Thomas, Summers TJ, Lee-Lin SQ, Maduro VVB, Idol JR, Prasad AB, Ryan JF, Touchman JW, Bouffard GG, Thomas PJ, Beckstrom-Sternberg SM, Blakesley RW, McDowell JC, Dietrich NL, Green ED

THE WHOLE GENOME ASSEMBLY OF MOUSE AND ITS IMPLICATIONS
Eugene W. Myers, Sutton G, Mural R, Li P, Yandell M, Halpern A, Smith H, Venter JC

LARGE-SCALE ANALYSIS OF THE MOUSE TRANSCRIPTOME
Tim Wiltshire, Walker J, Hakak Y, Su A, Ching K, Hogenesch J, Cooke P, Schultz P, Patapoutian A, Moqrich A

A DNA MICROARRAY SCREEN FOR GENES FUNCTIONING IN MAMMALIAN SEXUAL DEVELOPMENT
Lee Smith, Siggers P, Van Hateren N, Larder R, Walsh J, Stephens R, Freeman T, Greenfield A

PPI NETWORK VIEWER: ANALYSIS OF 500 PROTEIN-PROTEIN INTERACTIONS OBTAINED FROM RIKEN MOUSE FULL-LENGTH cDNA
Harukazu Suzuki, Saito R, Kanamori M, Miki R, Kagawa I, Bono H, Okazaki Y, Hayashizaki Y

EXPRESSION GENE TRAP MUTAGENESIS DEFINES DEVELOPMENTALLY REQUIRED GENES
William L Stanford, Bernstein A, Cohn JB

USING THE PUFFERFISH DNA SEQUENCE TO ANALYZE MAMMALIAN GENOMES
Jean Weissenbach, Olivier Jaillon, Michael Levy, Hugues Roest Crollius, Alain Bernot, Laurence Bouneau, Cécile Fischer, Catherine Ozouf-Costaz, William Saurin

ANNOTATING VERTEBRATE GENOME SEQUENCES
Tim Hubbard

MOUSE GENOME RESOURCES AT NCBI
Deanna Church, Maglott D, Shkeda A, Chen H-C, Schuler GD

INTEGRATING COMPUTATIONAL AND HUMAN-CURATED ANNOTATIONS FOR THE MOUSE GENOME
Carol Bult, King BL, Zhu YS, Baldarelli R, Ramachandran S, Bradt D, Cousins S, Beal J, Mani P, Kadin J and the Mouse Genome Informatics Staff

FUNCTIONAL STUDIES OF PROTEINS THAT BIND TO METHYLATED DNA
Adrian Bird, Brian Hendrich, Jacky Guy, Egor Prokhortchouk, Anna Prokhortchouk, Helle Jørgensen

A DEFECT IN A NOVEL NEK-FAMILY KINASE CAUSES CYSTIC DISEASE IN THE MOUSE AND IN ZEBRAFISH
David Beier, Liu S, Lu W, Kuida S, Obara-Ishihara T, Drummond I

THE WLD GENE: A UNIQUE NEUROPROTECTIVE FACTOR FOR AXONS
Michael Coleman, Mack TGA, Reiner M, Beirowski B, Mi W, Emanuelli M, Wagner D, Thomson D, Gillingwater T, Conforti L, Fernando FS, Tarlton A, Addicks K, Magni G, Perry VH, Ribchester RR

MUTATION OF A NOVEL GENE RESULTS IN ABNORMAL DEVELOPMENT OF SPERMATID FLAGELLUM, REDUCED ADULT BODY FAT MASS AND LOSS OF INTER-MALE AGGRESSION IN MICE
Grant MacGregor, Campbell P, Waymire K, Heier R, Sharer C, Day D, Friedrich G, Burmeister M, Bartness T, Russell L, Young L, Zimmer M, Jenne D

IDENTIFICATION OF A GENE INVOLVED WITH STEREOCILIA ELONGATION : POSITIONAL CLONING OF THE MOUSE wi DEAFNESS LOCUS
Philomena Mburu, Varela-Carver A.,Holme RH, Hardisty RE, White D, Paige A, Fleming J, Rogers M, Kiernan BW, Steel KP, Brown SDM

POSITIONAL CLONING OF THE MOUSE SACCHARIN PREFERENCE (SAC) LOCUS
Alexander Bachmanov, Li X, Reed DR, Ohmen JD, Li S, Chen Z, Tordoff MG, 2&de Jong PJ, Wu C, West DB, Chatterjee A, Ross DA, Beauchamp GK

IDENTIFICATION OF THE MOUSE UNDERWHITE (uw) GENE AND ITS HUMAN ORTHOLOGUE: OCULOCUTANEOUS ALBINISM TYPE 4 (OCA
Murray Brilliant, Newton JM, King RA, Gardner JM, Hagiwara N, Cohen-Barak O, Tran WN, Davisson MT

THE MELANOSOME TRANSPORT DEFECTS OBSERVED IN LEADEN MICE ARE CAUSED BY MUTATIONS IN MLPH, A NOVEL MEMBER OF THE RAB EFFECTOR FAMILY
Lydia Matesic, Wu X, Yip R, Reuss AE, Swing DA, O'Sullivan TN, Fletcher CF, Hammer III JA, Copeland NG, Jenkins NA

TRUNCATION OF LIM HOMEOBOX TRANSCRIPTION FACTOR Lmx1a RESULTS IN ABNORMAL DEVELOMENT OF THE CENTRAL NERVOUS SYSTEM OF qc/qc RAT
Kazuhiro Kitada, Muraguchi T, Ueno M, Kuwamura M, Guénet JL, Serikawa T

A TRUNCATED FORM OF L1 2'-5'-OLIGO- ADENYLATE SYNTHETASE IS ASSOCIATED WITH GENETIC SUSCEPTIBILITY TO FLAVIVIRUS INFECTIONS
Tomoji Mashimo, Simon-Chazottes D, Lucas M, Frenkiel MP, Montagutelli X, Deubel V, Desprès P, Guénet JL

MURINE MUSCULAR DYSTROPHY PHENOTYPE CAUSED BY A GLYCOSYLTRANSFERASE MUTATION AND DISRUPTION OF THE DYSTROPHIN ASSOCIATED GLYCOPROTEIN COMPLEX
Pam Grewal, Bittner R, Hewitt J

LARGE-SCALE ISOLATION AND RAPID MAPPING OF RECESSIVE MUTATIONS USING A MOUSE BALANCER CHROMOSOME
Monica Justice, Salinger A, Clark A, Hentges K, Box N, Holdsworth A, Maffucci J, Ross M, Liu B, Behringer B, Bradley, A Justice M

NEW MOUSE MODELS FOR HEARING AND BALANCE DEFECTS FROM THE EUROPEAN MUTAGENESIS PROGRAMMES
Karen P Steel, Steel K, Kiernan A, Erven A, Rhodes C, Tsai H, Hardisty R, Nolan P, Peters J, Brown SDM, Hunter AJ, Ahituv N, Hertzano R, Vreugde S, Avraham K, Fuchs H, Balling R, Hrabé de Angelis M, JL Guénet

PHENOTYPIC ANALYSIS AND CHROMOSOMAL MAPPING OF MOUSE MUTANTS WITH IMMUNOLOGICAL DEFECT GENERATED BY ENU-MUTAGENESIS
Heinrich Flaswinkel, Rathkolb, B, Faerber, C, Servatius, A, Soewarto, D, Kremmer, E, Sandholzer, N, Hrabe de Angelis, M, Balling, R, Wolf, E, Pfeffer, K

MOUSE INFERTILITY AND GENOME INSTABILITY MUTANTS
John Schimenti, Libby B, Ward J, Munroe R, Shima N, Bergstrom R

A GENOTYPE-BASED SCREEN IN MOUSE EMBRYONIC STEM CELLS FOR ENU-INDUCED MUTATIONS IN THE SMAD2 LOCUS
Jay Vivian, Chen Y, Magnuson T

A GENE-DRIVEN APPROACH TO THE IDENTIFICATION OF ENU MUTANTS IN THE MOUSE CONNEXIN 26 GENE
Emma Coghill, Hugill A, Hunter AJ, Cox R, Brown SDM

FACTORS AFFECTING THE DEVELOPMENT OF CLONED EMBRYOS
Ian Wilmut

EPIGENETIC REPROGRAMMING AFTER NUCLEAR TRANSFER
Kevin Eggan, Humpherys D, Akutsu H, Hochedlinger K, Rideout III W, Yanagimachi R, Jaenisch R

IMPRINTED X-INACTIVATION MAINTAINED BY A MOUSE POLYCOMB GROUP GENE
Jesse Mager, Jainbo Wang, Terry Magnuson

Mesdc2: A NOVEL MOLECULE REQUIRED FOR PATTERNING IN THE EARLY MOUSE EMBRYO
Bernadette Holdener, Lee L, Zhang L, Brown K, DeRossi C

MUTATION ANALYSIS OF DARK SKIN AND HAIR
Karen Fitch, McGowan KA, Van Raamsdonk CD, Fuchs H, Hrabé de Angelis M, Barsh GS

NEURODEGENERATION AND COAT COLOR DEFECTS IN THE ATTRACTIN PATHWAY
Teresa Gunn, He L, Barsh GS

A MUTATION IN P53 BINDING PROTEIN RELATED PROTEIN CAUSES DILATED CARDIOMYOPATHY AND SKIN DEFECTS IN WA3 MICE
Bruce Herron, Rao C, Pacella L, Semsarian C, Seidman C, Stubbs L, Millar S, Beier DR

THE PUDGY/SPONDYLOCOSTAL DYSOSTOSIS GENE DELTA-LIKE 3 IS REQUIRED FOR CYCLING IN SOMITOGENESIS & IS DYNAMICALLY EXPRESSED IN NEURAL DEVELOPMENT
Kenro Kusumi, Dunwoodie, S., Krumlauf, R.

DISRUPTION OF THE MOUSE CTCF GENE RESULTS IN EARLY PREIMPLANTATION LETHALITY
Galina N.Filippova, Sara Fagerlie, James M. Moore, Kevin P. Foley, Joanne Whitehead Chris Kemp, Rolf Ohlsson, Victor Lobanenkov

DISRUPTION OF THE aN-CATENIN GENE IN CEREBELLAR DEFICIENT FOLIA MUTANT MICE RESULTS IN CEREBELLAR AND HIPPOCAMPAL LAMINATION DEFECTS
Susan Ackerman, Park C, Edgar JH, Longo-Guess CM

IDENTIFICATION OF MOUSE AND HUMAN CANCER MODIFIER GENES USING MOUSE MODELS
Alain Balmain

IDENTIFICATION OF QTL DETERMINANTS OF TYPE 2 DIABETES SUBPHENOTYPES IN MICE
Ayo Toye, Goldsworthy M, Bentley L, Moir L, Ritson D, Haynes A.E, Mijat V, Cox R.

IDENTIFICATION OF MULTIPLE QUANTITATIVE TRAIT LOCI LINKED TO PRION DISEASE INCUBATION TIME
Sarah Lloyd, Onwuazor O, Uphill J, Beck J, Farrall M, Targonski P, Collinge J, Fisher E

A QTL UNDERLYING HEMATOPOIETIC STEM CELL PROLIFERATION COLOCALIZES WITH A CLUSTER OF DIFFERENTIALLY EXPRESSED GENES AND REGIONS OF INCREASED MEIOTIC RECOMBINATION
Leonid Bystrykh, Weersing E, Geiger H, Ivanova N, Van Zant G, Lemischka I, Vellenga E, de Haan G

GENOTYPE: PHENOTYPE CORRELATIONS IN MOUSE MODESL ILLUMINATE MOLECULAR MECHANISMS OF DOWN SYNDROME
Roger Reeves, Richtsmeier J, Zumwalt A, Carlson E, Epstein C

RECOMBINANT INBRED INTERCROSS (RIX) MAPPING: A NEW APPROACH EXTENDING THE POWER OF EXISTING MOUSE RESOURCES
David Threadgill, Airey DC, Lu L, Manly KF, Williams RW