International Mammalian Genome Society

17th International Mouse Genome Conference

9-12 November 2003, Braunschweig, Germany

Plenary Presentations * Oral Presentations *
Poster Presentations: Behavioural Genetics and Genomics * Development and Stem Cells * Functional Genome Analysis * Mouse Models of Human Disease * Mouse System Biology Bioinformatics * Multigenic and Multifactorial Trait Analysis * Nutrition and Metabolic Disease * Phenotyping Methods Imaging * The Genetics and Genomics of Infectious Disease *
Verne Chapman Memorial Lecture * Table of Contents * Sponsor/Exhibitor List * Awards * Photographs

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POSTER 153 - MOUSE GENOME ANALYSIS AND ANNOTATION AT THE SANGER INSTITUTE HAVANA GROUP

Wilming L
Havana Group, Wellcome Trust Genome Campus

Co-Authors:
Institutions:

The Sanger Institute is responsible for the sequencing, analysis and annotation of 25% of the mouse genome comprising chromosomes 2, 4, 11 and X. As part of the UK MRC Mouse Sequencing Consortium, regions of chromosome 2 (WAGR) and 4 (brown deletion complex) are sequenced by the HGMP and analyzed in collaboration with the MRC (Edinburgh) and a region of chromosome 13 (Del36h) sequenced at the Sanger Institute and analyzed in collaboration with the MRC (Harwell). Analysis and annotation is performed by the Institute's Havana group. Working to the standards agreed upon between different sequencing centers worldwide during the HAWK workshops (http://www.sanger.ac.uk/HGP/havana/hawk.shtml), it aims to deliver gold standard manual annotation, which will be available through the Ensembl-like VEGA browser.

I will present an overview of the analysis and annotation of finished mouse genomic regions, highlighting interesting and unusual gene structures, and discussing the benefits of our manual annotation.