International Mammalian Genome Society

17th International Mouse Genome Conference

9-12 November 2003, Braunschweig, Germany

Plenary Presentations * Oral Presentations *
Poster Presentations: Behavioural Genetics and Genomics * Development and Stem Cells * Functional Genome Analysis * Mouse Models of Human Disease * Mouse System Biology Bioinformatics * Multigenic and Multifactorial Trait Analysis * Nutrition and Metabolic Disease * Phenotyping Methods Imaging * The Genetics and Genomics of Infectious Disease *
Verne Chapman Memorial Lecture * Table of Contents * Sponsor/Exhibitor List * Awards * Photographs

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Oral Presentations

IDENTIFICATION OF SEGMENTAL DUPLICATION WITHIN THE MOUSE GENOME
Church DM, Bailey J A, Agarwala R, Eichler E E

TOWARDS A SNP-BASED MOUSE HAPLOTYPE MAP
Pletcher M T, Batalov S, McClurg P, Barnes S W, Wiltshire T

FUNCTIONAL ANALYSIS OF THE MOUSE GENOME BY GENE TRAP MUTAGENESIS
Floss T, Seisenberger C, Ruiz P, van Sloun P, Schnütgen F, Füchtbauer EM, Franz Vauti, Arnold HH, Hansen J, von Melchner H, Wurst W.

FUNCTIONAL ANNOTATION OF MUTANT MOUSE ES CELL LINES BY EXPRESSION PROFILING
Symula D J, Curley B

TOWARD A WHOLE-GENOME MOUSE EXPRESSION MICROARRAY: USING THE NIA MOUSE GENE INDEX TO EXPAND THE NIA MOUSE DEVELOPMENT AND NIEHS TOXICOGENOMICS MICROARRAY PLATFORMS
Carter M G, Sharov A A, Dudekula D B, VanBuren V, Qian Y, Ko, M S H

GENE EXPRESSION PATTERNS OF THE MOUSE TRANSCRIPTOME
Wiltshire T, Walker J, Su A, Batalov S, Hogenesch J

IDENTIFICATION OF NOVEL DELTA/NOTCH TARGET GENES DURING MOUSE EMBRYONIC DEVELOPMENT USING DNA-CHIP AND PROTEIN EXPRESSION PROFILING
Machka C, Halder T, Harder A, Hrabe de Angelis M, Beckers J

HIPPOCAMPAL GENE EXPRESSION IN HETEROGENEOUS STOCK (HS) MICE SELECTED FOR LOW, MID AND HIGH PERFORMANCE ON COGNITIVE TASKS
Paya-Cano JL, Fernandes C, Liu L, Rijsdijk F, Plomin R, Schalkwyk LC

ANXIETY SUSCEPTIBILITY QTL IN MOUSE MODEL: HOW FAR ARE WE FROM DISCOVERING A QT GENE?
Yalcin B, Fullerton J, Miller S, Mott R, Flint J

A FUNCTIONAL SINGLE NUCLEOTIDE POLYMORPHISM IN CADHERIN 23 IS ASSOCIATED WITH POLYGENIC INHERITANCE AND GENETIC MODIFICATION OF SENSORINEURAL HEARING LOSS IN MICE
Noben-Trauth K, Zheng Q Y, Johnson K R

QUANTITATIVE TRAIT LOCI FOR HDL-CHOLESTEROL
Paigen B, Wang X, Lyons M, Korstanje R

A LOCUS ON CHROMOSOME 7 DETERMINES MARKED UPREGULATION OF OSTEOPONTIN IN MICE WITH DYSTROPHIC CARDIAC CALCIFICATION
Korff S, Aherrahrou Z, Kaczmarek P M, Axtner S B, Jurat A, Doehring L C, Weichenhan D, Katus H A, Ivandic B T

ODSM1 A LOCUS WITH MATERNAL EFFECT, SUPPRESS THE SEX REVERSAL IN THE ODSEX (ODS) MODEL
Poirier C, Qin Y, Truong C, Agoulnik A I, Bishop CE

REPRODUCTIVE ISOLATION AS A COMPLEX TRAIT: TOWARDS GENETIC ARCHITECTURE OF HYBRID STERILITY IN THE MOUSE
Forejt J, Trachtulec Z, Aixnerová R, Gregorova S, Krizan J, Divina P, Vlcek C, Paces V, Vacík T, Jansa P

DELETION OF THE ENDOGENOUS MOUSE SNCA GENE MARKEDLY EXACERBATES SYNUCLEINOPATHY IN TRANSGENIC MICE EXPRESSING Ala53>Thr HUMAN A-SYNUCLEIN
Cabin D E, Gispert-Sanchez S, Murphy D, Auburger G, Myers R, Nussbaum R

GENETIC CONTROL OF ADRENAL DEVELOPMENT AND FUNCTION: INTERACTION OF DAX1 AND STEROIDOGENIC FACTOR-1
Keegan C, Shah S, Jameson L, Hammer G

UTILISING THE P57^KIP2 KNOCKOUT MOUSE TO UNDERSTAND CELL GROWTH PERTURBATION IN BECKWITH - WIEDEMANN SYNDROME
Lamprill E F, Digger K, Miller N, Barton S C, John R M, Surani A, Schofield P N

PHENOTYPIC ANALYSIS AND CHROMOSOMAL MAPPING OF MOUSE MUTANTS WITH CLINICALLY RELEVANT ALTERATIONS OF THE IMMUNE SYSTEM
Flaswinkel H, Rathkolb B, Reindl W, Howaldt M, Jakob T, Köllisch G, Sandholzer N, Soewarto D, Krebs O, Kremmer E, Hrabe de Angelis M, Balling R, Pfeffer K, Wolf E

DYSREGULATION OF T CELL RESPONSES IN MICE WITH T CELL-SPECIFIC INACTIVATION OF THE IL-10 GENE
Mueller W, Roers A, Siewe L, Strittmatter E, Deckert M, Schlüter D, Stenzel W, Gruber AD, Krieg T, Rajewsky K

FROM THE MIN MOUSE MODEL TO STUDIES OF THE INTESTINAL EPITHELIUM AND ITS NEOPLASMS IN THE MOUSE AND THE HUMAN
Dove W F, Chen X, Clipson L, Ehrhardt W, Haigis K, Halberg R, Hoff P, Kwong L, Newton M, Meyerand E, Pasch C, Shedlovsky A, Thliveris A, Weichert J, White A

NEW MOUSE MODELS OF TYPE II DIABETES FROM A SENSITISED N-ETHYL-N-NITROSOUREA (ENU) MUTAGENESIS SCREEN
Goldsworthy M, Mijat V, Haynes A E, Hugill A, Paul C L, Bentley E, Horner E J, Anstee Q M, Cox R D

UBIQUITINATION OF NOTCH PATHWAY DELTA LIGAND AND DEATH-ASSOCIATED PROTEIN KINASE IS ESSENTIAL TO MAINTAIN EMBRYONIC NEUROEPITHELIAL STEM CELLS
Barsi J C, Rajendra R, Wu J I, Artzt K

TARGETED DELETION OF FENS1 IN MICE LEADS TO INABILITY OF SPERM TO FERTILIZE
Bishop C, Rohozinski j, Ty M, Matzuk M, El Din N, Lamb D

A DEFECT IN A NOVEL ADAMTS FAMILY MEMBER IS THE CAUSE OF THE BELTED WHITE-SPOTTING MUTATION
Beier DR, Rao C, Foernzler D, Loftus S, Liu S, McPherson J, Jungers K, Apte S, Pavan W

NOVEL COMPONENTS OF DELTA-NOTCH SIGNAL TRANSDUCTION
Pfister S, Przemeck G K, Gerber J K, Beckers J, Adamski J, Hrabe de Angelis M

EUMORPHIA -- DEVELOPING NEW APPROACHES TO MOUSE PHENOTYPING
Brown SDM

THE GERMAN MOUSE CLINIC -- A PLATFORM FOR COMPREHENSIVE, STANDARDIZED PHENOTYPING OF MOUSE MUTANTS
Hrabe de Angelis M, Fuchs H, Gailus-Durner V, Lengger C, Reinhard C, Schulz H, Calzada-Wack J, Elvert R, Dalke C, Franz, Grundner-Culemann E, Hölter S, Javaheri A, Kalaydijev S, Klempt M, Kunder S, Mijalski T, Pedersen V, Prehn C, Radz I, Schneider I, Ehrhardt N, Zybill C, Bader M, Birchmeier-Kohler C, Brielmeier M, Groβ V, Hübner N, Lengeling A, Lewin G, Morano I, Müller W, Reitmeir P, Schmidt J, Willnow T, Adamski J, Beckers J, Behrendt H, Busch D, Favor J, Gekeler F, Graw J, Heldmaier G, Heyder J, Höfler H, Klingenspor M, Klopstock T, Meitinger T, Ollert M, Quintanilla-Martinez L, Wolf E, Wurst W, Zimmer A

HIGH-THROUGHPUT, NON-INVASIVE PROTOCOLS PROVIDE RELIABLE METHODS FOR EVALUATING HEART, LUNG AND SLEEP FUNCTION IN MICE
Svenson K L, Galante R, Pack A I, Walker J K, Schwartz D A, Barker J E, Peters L L

COMPARATIVE PATHOLOGY FOR FUNCTIONAL GENOMICS INITIATIVES
Brayton C

WOUND REPAIR AN IMPORTANT PATHWAY IN RESISTANCE TO L. MAJOR INFECTION
Foote S, Handman E, Ellso C, Speed T, Smyth G, Sakthianandeswaren A, Curtis J, Kumar B

THE IDENTIFICATION OF GENES CONTROLLING IMMUNE FUNCTION IN THE MOUSE BY GENOME-WIDE ENU MUTAGENESIS
Brunkow M E, Staehling-Hampton K, Appleby M, Gilchrist J, Britschgi T, Charmley P, Ebeling C, Howard T, Martin K, McEuen M, Paeper B, Proll S, Snell A, Tang P, Tittel P, Wasnick M, Wiegand N, Bouck J, Ramsdell F, Carlson G, Schatzman R

HOST-DEPENDENT VARIATION IN COLONIZATION BY THE GASTROINTESTINAL FLORA
Threadgill D W, Alexander A D, Hench G

ABNORMAL CONNECTIVE TISSUE REMODELING IN MICE DEFICIENT FOR RELAXIN RECEPTOR
Agoulnik A, Kamat A, Feng S, Bogatcheva N, Bishop C

PHYSIOLOGICAL BASIS OF RESISTANCE TO DIETARY OBESITY SEEN IN THE B6.LP MOUSE, CONGENIC FOR A REGION ON CHROMOSOME 2
Zuberi A R, MacGowan J, Richards B, Krishnan B

DEVELOPING PITUITARY TRANSCRIPTOME
Camper SA, Brinkmeier ML, Carninci P, Lyons RH, Shiraki T, Arakawa T, Kawai J, Hayashizaki Y

INTEGRATIVE TRANSOMIC ANALYSIS STRATEGIES REVEAL NOVEL INSIGHTS INTO POTENTIALLY IMPORTANT MOLECULAR PATHWAYS FOR MAMMARY TUMOR METASTASIS
Hunter K, Park Y-G, Yang H, Zhang J, Lukes L, Lancaster M, Buetow K

MAKING SENSE OF SEQUENCE: INTEGRATING BIOLOGICAL KNOWLEDGE WITH THE MOUSE GENOME
Bult CJ, Bradt D, Reed D, Zhu S, Qi D, Sinclair B, Blake J A, Ringwald M, Eppig JT, Richardson J E, Kadin J A, The Mouse Genome Informatics Group

AN INTEGRATED APPROACH TO MOUSE FUNCTIONAL GENOMIC DATA
Hedeler C, Else K J, Paton N W