18th International Mouse Genome Conference (2004)

18th International Mouse Genome Conference

17-22 October 2004, Seattle, USA

Plenary Presentations * Oral Presentations * Poster Abstracts * Photos
Verne Chapman Memorial Lecture * Table of Contents * Attendees * Awards

Epigenetics and Modifiers

POSTERS 31 - 53

31. THE SEARCH FOR HUNTINGTON'S DISEASE MODIFIERS IN THE MOUSE
Acevedo A ¹, Chrobot N ¹, Rubinsztein DC ², Brown SD ¹
¹ MRC Mammalian Genetics Unit, Harwell, United Kingdom, ² Cambridge Institute for Medical Research, Cambridge, United Kingdom

32. COORDINATION OF GROWTH AND METABOLISM BY THE IMPRINTED GRB10 GENE
Ward A, Koumanov F, Charalambous M, Garfield A, Allsop JE, Moorwood K, Smith FM
University of Bath, Bath, United Kingdom

33. SENSITIZED MUTAGENESIS SCREEN FOR MODIFIERS OF THE DELTA/NOTCH PATHWAY IN THE MOUSE
Rubio-Aliaga I, Soewarto D, Wagner S, Przemeck G, Fuchs H, Hrabé de Angelis M
GSF Research Center - Institute of Experimental Genetics, Neuherberg/Munich, Germany

34. COORDINATION OF GROWTH AND METABOLISM BY THE IMPRINTED GRB10 GENE
Smith FM ¹, Charalambous M ², Koumanov F ¹, Garfield A ¹, Ward A ¹
¹ Centre for Regenerative Medicine, University of Bath, Bath, United Kingdom, ² Centre for Diabetes and Endocrinology, Division of Medicine, London, United Kingdom

35. FINE MAPPING PRION DISEASE INCUBATION TIME QTL USING HETEROGENEOUS STOCK MICE
Lloyd SE ¹, Maytham ELG ¹, Thompson S ¹, Mott R ², Fisher EMC ¹, Collinge J ¹
¹ MRC Prion Unit, London, United Kingdom, ² The Wellcome Trust Centre for Human Genetics, Oxford, United Kingdom

36. IDENTIFICATION OF NOVEL IMPRINTED GENES ON MOUSE CHROMOSOMES 7 AND 18
Woodfine K ¹, Choi JD ¹, Wood AJ ¹, Collins JN ², Oakey RJ ¹
¹ Division of Medical Genetics, GKT School of Medicine, London, United Kingdom, ² Division of Human Genetics, The Children’s Hospital of Philadelphia, Philadelphia, United States

37. SUPPRESSORS AND ENHANCERS OF TESTICULAR CANCER SUSCEPTIBILITY IN DOUBLE-MUTANT MICE
Lam MYJ, Youngren KK, Nadeau JH
Case Western Reserve University, Cleveland, United States

38. MODIFIERS OF THE DDK SYNDROME RESULT IN THE DOMINANT RESCUE OF EMBRYONIC LETHALITY
Ideraabdullah FY, Kim K, Pardo-Manuel de Villena F
Dept of Genetics, UNC-Chapel Hill, Chapel Hill, United States

39. THE REQUIREMENT FOR EED IN AUTOSOMAL GENOMIC IMPRINTING MAY BE TISSUE SPECIFIC
Chamberlain SJ, Montgomery ND, Kalantry S, Magnuson T
Department of Genetics, University of North Carolina-Chapel Hill, Chapel Hill, NC, United States

40. PREDISPOSITION TO MOUSE THYMIC LYMPHOMAS DEPENDS ON COMMON VARIANT ALLELES OF MTF-1 (METAL RESPONSIVE TRANSCRIPTION FACTOR-1)
Kominami R ¹, Tamura Y ¹, Maruyama M ¹, Mishima Y ¹, Schaffner W ²
¹ Niigata University, Graduate School of Medical and Dental Sciences, Niigata, Japan, ² Institute for Molecular Biology, University of Zurich, Zurich, Switzerland

41. EVOLUTIONARILY CONSERVED SEQUENCE ELEMENTS THAT POSITIVELY REGULATE INTERFERON GAMMA EXPRESSION IN T CELLS
Shnyreva M ¹, Weaver WM ¹, Blanchette M ³, Taylor SL ², Fitzpatrick DR ², Tompa M ¹, Wilson CB ¹
¹ University of Washington, Seattle, United States, ² Amgen Corporation, Seattle, United States, ³ McGill University, Montreal, Canada

42. MODIFIER LOCI THAT INFLUENCE TPA SKIN TUMOR PROMOTION SUSCEPTIBILITY IN GENETIC CROSSES OF DBA/2 WITH C57BL/6 MICE
Angel JM, Abel EL, Riggs PK, Elizondo L, Caballero M, DiGiovanni J
Univ Texas, MD Anderson Cancer Center, Science Park-Research Division, Smithville, United States

43. MOUSE HAIRY EARS (EH) INVERSION MUTATION DISRUPTS NO GENE TRANSCRIPTS, BUT EXPRESSION OF HOXC GENES IN SKIN IS DISTURBED
Mentzer S ¹, Sundberg J ², Cacheiro N ¹, Chao H ³, Carpenter D ¹, Johnson D ¹, Rinchik E ³, You Y ¹
¹ Oak Ridge National Laboratory, Oak Ridge, United States, ² The Jackson Laboratory, Bar Harbor, United States, ³ University of Tennessee, Knoxville, United States

44. DEVELOPMENTAL PROFILE OF DNA METHYLATION AND GENE EXPRESSION AT THE H19 LOCUS IN MICE LACKING SEQUENCE REQUIRED FOR GENOMIC IMPRINTING
Thorvaldsen J , Fedoriw A , Yang G , Bartolomei M
University of Pennsylvania, Philadelphia, United States

45. CURRENT PROGRESS IN SCREENING FOR MUTANTS AFFECTING GENOMIC IMPRINTING IN THE RIKEN-GSC PROJECT
Suzuki T ¹, Furuumi H ², Hashimoto M ³, Kyouno S ⁴, Nagashima A ¹, Kumaki K ², Kaneda H ¹, Gondo Y ⁵, Noda T ¹, Wakana S ¹, Ishino F ⁴, Sasaki H ², Shiroishi T ¹
¹ Mouse Functional Genomics Research Group, Genomics Science Center (GSC), RIKEN Yokohama Institute, Yokohama, Japan, ² Department of Integrated Genetics, National Institute of Genetics, Mishima, Japan, ³ Gene Research Center, Tokyo Institute of Technology, Yokohama, Japan, ⁴ Department of Epigenetics, Medical Research Center, Tokyo Medical and Dental University, Tokyo, Japan, ⁵ Population and Quantitative Genomics Team, GSC, RIKEN, Yokohama, Japan

46. ANALYSIS OF THE CANDIDATE REGION AND CANDIDATE GENES RESPONSIBLE FOR THE DDK SYNDROME OF EMBRYONIC LETHALITY
de la Casa-Esperon E ¹, Gimelbrant A ³, Adey B ¹, Briscoe T ¹, Hao L ¹, Wu G ¹, Chess A ³, Pardo-Manuel de Villena F ², Sapienza C ¹
¹ Fels Institute, Temple University School of Medicine, Philadelphia, PA, United States, ² Department of Genetics, UNC-Chapel Hill, Chapel Hill, NC, United States, ³ Whitehead Institute for Biomedical Research, MIT, Cambridge, MA, United States

47. GENOME-WIDE ASSOCIATION ANALYSIS IDENTIFIES NOVEL MODIFIER LOCI OF HIRSCHSPRUNG DISEASE IN SOX10^DOM MICE
Owens SE ¹, Broman KW ², Smith JR ¹, Southard-Smith EM ¹
¹ Vanderbilt University, Nashville, United States, ² Johns Hopkins University, Baltimore, United States

48. A SENSITIZED ENU MUTAGENESIS SCREEN FOR DOMINANT GENETIC MODIFIERS OF THROMBOSIS IN THE FACTOR V LEIDEN MOUSE
Westrick RJ ¹, Manning SL ², Dobies SL ¹, Peterson AL ², Siemieniak DR ², Korepta LM ¹, Ginsburg D ²
¹ University of Michigan, Ann Arbor, United States, ² Howard Hughes Medical Institute, Ann Arbor, United States

49. MODIFIERS OF AGANGLIONIC MEGACOLON IDENTIFIED BY EVALUATION OF CANDIDATE GENES IN THE SOX10^DOM HIRSCHSPRUNG DISEASE MODEL
Cantrell VA, Owens SE, Chandler RL, Bradley KM, Smith JR, Southard-Smith EM
Vanderbilt University, Nashville, United States

50. CHROMATIN DOMAINS THAT ESCAPE X INACTIVATION CHARACTERIZED BY CTCF BINDING AND HISTONE MODIFICATIONS
Cheng MK ¹, Filippova GN ², Disteche CM ¹
¹ University of Washington, Seattle, United States, ² Fred Hutchinson Cancer Research Center, Seattle, United States

51. SNP AND SSLP HAPLOTYPES, TUMOR MICROARRAYS, AND CONGENIC RECOMBINANTS IN THE IDENTIFICATION OF HCS7, A POTENT LIVER CANCER MODIFIER
Bilger A, Schneider A, Leutkehoelter K, Sundlov T, Drinkwater N
University of Wisconsin Medical School, Madison, United States

52. IDENTIFICATION OF GENES INFLUENCING PLASMA VON WILLEBRAND FACTOR LEVELS IN MICE
Lemmerhirt HL ¹, Ginsburg D ²
¹ Department of Human Genetics, The University of Michigan, Ann Arbor, United States, ² Howard Hughes Medical Institutue, Ann Arbor, United States

International Mammalian Genome Society